The Primal Podcast Ep 151 - Dr Myhill | Tired, Stressed, or Foggy? These 3 Supplements Are Proven To Work
11 snips
Feb 7, 2026 
Dr. Sarah Myhill, physician and pioneer in functional medicine focused on chronic fatigue and mitochondrial health. She explores mitochondrial failure as a root of unexplained tiredness. She discusses how ultra‑processed foods and caffeine harm energy, the role of thyroid and environmental toxins, gut fermentation, and a paleo‑ketogenic approach plus simple supplements to rebuild energy.
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Tobacco Science Turned To Food Addiction
- Dr. Myhill recounts tobacco companies buying food firms to make ultra-processed foods addictive by mimicking tobacco science.
- She uses this to explain why modern processed foods drive overeating and metabolic disease.
Use Caffeine Sparingly
- Avoid chronic use of caffeine as it stimulates mitochondria short-term but exhausts them long-term.
- Reserve caffeine for occasional performance needs followed by rest to allow recovery.
Fatigue Is An Early Warning For Many Diseases
- Mitochondrial dysfunction is implicated across many diseases including diabetes, dementia, heart disease and cancer.
- Fatigue is an early signal that energy systems may be failing and predicts broader disease risk.
