The Resetter Podcast with Dr. Mindy Your Brain on Ketones: The New Science Linking Metabolic Health, Mental Health, and the Power of Ketosis with Dr. Georgia Ede
Apr 8, 2026
Dr. Georgia Ede, a Harvard-trained psychiatrist and leader in nutritional psychiatry, explores how ketones and metabolic health shape brain function. She discusses the brain as a hybrid engine using glucose and ketones. Topics include links between insulin resistance and mood disorders, ketone targets for serious mental illness, overnight ketosis for brain repair, menopause and brain metabolism, and practical paths to achieve ketosis.
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Target 1.0–3.0 mmol/L For Mental Health
- Aim for blood ketones between 1.0 and 3.0 mmol/L when treating serious mental illnesses.
- Use that window as a starting point then personalize; some patients feel better at slightly lower or higher levels.
Give Ketosis Six Weeks Before Judging
- Give a ketogenic intervention at least 4–6 weeks (optimally six) to assess mental health response, with many improving by three weeks.
- Expect an adaptation phase; those who pass week three often find appetite control and energy stabilize.
Researcher Recovered Then Refused To Stop Keto
- Ian Campbell, a musician-turned-researcher with bipolar disorder, improved within three days on low-carb and later studied ketogenic diets.
- In a 20-person study, average ketones ≈1.3 mmol/L and seven participants refused to stop the diet after the trial.
