TWiV 1230: Clinical update with Dr. Daniel Griffin

Jun 28, 2025

Dr. Daniel Griffin, a physician and infectious diseases expert, joins Vincent Racaniello for an informative discussion. They express concerns over RFK's impact on vaccine policies, stressing the risks of neglecting immunization practices. The duo reviews alarming data on RSV, influenza, and COVID-19, along with recent advancements in monoclonal antibody treatments. They also explore emerging long COVID therapies and the importance of maintaining global vaccination efforts while addressing vaccine hesitancy. A call to action for scientific integrity resonates throughout the conversation.

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INSIGHT

US Adults Support Vaccines, Distrust Agencies

Majority of US adults believe vaccines are safe, effective, and needed to protect others but trust in government agencies is declining.
This erosion in trust reflects political challenges impacting vaccine acceptance.

INSIGHT

US Retreat Threatens Global Vaccinations

US withdrawal from global vaccine funding jeopardizes child immunization in poor countries and risks resurgence of diseases.
Bill Gates and allies pledge funding, but gaps remain significant.

INSIGHT

Poultry Flu Vaccination Debate

Poultry vaccination against avian flu is debated due to asymptomatic infections possibly harming trade.
Despite challenges, poultry outbreaks severely threaten egg supply and animal health.

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In his weekly clinical update, Dr. Griffin with Vincent Racaniello are alarmed at how RFK is breaking his promise of not altering vaccine policies, and nonexistent data and studies are used by members of the ACIP to make changes to immunization practices in the absence of a CDC director, justification for not honoring the US commitment to GAVI and global public policies including support of routine childhood immunizations, placing millions of children at risk for the return of vaccine preventable diseases including polio outbreaks in Pappa New Guinea and increased circulation of wildtype type 1 poliovirus, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, approval of Merck’s anti-RSV mRNA monoclonal antibody, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, changes in COVID mRNA vaccine labeling and reframing of the science around the vaccine, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research

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Links for this episode

Jake Scott (Stanford University)
Vaccine Randomized control trials (Bradspellberg.com)
Vaccine RCT spreadsheet aims to show the data, dispel myths about vaccines (CIDRAP)
Vaccines-rcts (Bradspellberg.com)
CDC’s upcoming vaccine advisory meeting set up to sow distrust in vaccines (CIDRAP)
Next ACIP meeting (CDC: ACIP)
June meeting: MEETING OF THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP) (CDC: ACIP agenda)
Robert F Berman, PhD (UC Davis Health: Department of Neurological Surgery)
Transparency = nonexistent data: CDC advisers appears to cite nonexistent study to support claims about risk of vaccine preservative (CNN)
A C.D.C. Committee Just Voted Against Flu Shots With This Preservative. Is It Safe? (NY Times)
CDC vaccine advisory committee to review long-approved immunizations (STAT News)
Newly appointed CDC vaccine advisory committee holds first meeting, stirs more controversy (CIDRAP)
FDA approves clesrovimab to protect infants during first RSV season (Contemporary Pediatrics)
ACIP updates: Committee recommends clesrovimab for RSV, reaffirms routine influenza vaccination (Contemporary Pediatrics)
Susan Monarez (Wikipedia)
Robert F Kennedy Jr (Wikipedia)
Centers for Disease Control and Prevention (Wikipedia)
Who is in charge at the CDC (CDC: About CDC)
Do children REALLY need to be vaccinated? (Wall Street Journal)
U.S. Adults’ Views on Routine Childhood Vaccination (Harvard Opinion Research Program)
RFK Jr. declares US withdrawal from GAVI (YouTube)
Kennedy Withdraws U.S. Funding Pledge to International Vaccine Agency (NY Times)
Millions of children at risk as global vaccine rates fall (Guardian)
Global, regional, and national trends in routine childhood vaccination coverage from 1980 to 2023 with forecasts to 2030 (LANCET)
Polio this week: 47 WPV1 positive environmental samples this week! (GPEI)
H5 bird flu: current situation (CDC: Avian Influenza)
Cambodia logs fifth death from H5N1 avian flu as USDA weighs poultry vaccination (CIDRAP)
Cambodia reports 6th H5N1 bird flu case this year(BNO News)
USDA develops potential plan to vaccinate poultry for bird flu (Reuters)
Wastewater for measles (WasterWater Scan)
Measles cases and outbreaks (CDC Rubeola)
Weekly measles and rubella monitoring (Government of Canada)
Measles vaccine recommendations from NYP (jpg)
Measles (WHO)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Measles (CDC: Measles Rubeola)
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Respiratory virus activity levels (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
Novel Drug Approvals for 2025 (FDA)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (biRxiV)
Episode 184: Fool’s Gold: Reframing the Science…..reframing? (Apple Podcasts: Osterholm Update)
Children with Post COVID-19 Multisystem Inflammatory Syndrome Display Unique Pathophysiological Metabolic Phenotypes (Journal of Proteome Research)
FDA COVID mRNA vaccine labeling update (FDA)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusion center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
Managing healthcare staffing shortages (CDC)
Steroids,dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Stellate Ganglion Block for the Treatment of COVID-19−Induced Parosmia (JAMA Otolaryngology-Head& Neck Surgery)
Reaching out to US house representative
Letters read on TWiV 1230
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.