Health Report

Uncovering the brain circuit for creativity

10 snips
Dec 26, 2025
Haryana Dillon, a Professor of Psycho-Oncology focused on exercise after cancer, and Dr. Isaiah Kletnik, a Harvard cognitive neurologist studying neuroimaging of creativity, dive into fascinating discussions. They explore how neurodegenerative diseases can paradoxically enhance creativity, revealing a link between brain changes and artistic output. Dillon shares insights about an innovative exercise program significantly reducing colorectal cancer recurrence. The duo also touches on the potential of psychedelics to boost creativity by altering self-monitoring.
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INSIGHT

Exercise Cuts Colon Cancer Recurrence

  • A structured exercise program after colorectal cancer reduced recurrence and improved survival.
  • The trial found 80% disease-free survival versus 74% and a 37% reduction in mortality at eight years.
INSIGHT

Benefits Aren't Just About Weight Loss

  • Exercise benefits appeared independent of weight loss and may act via reduced inflammation or insulin resistance.
  • That suggests biological mechanisms beyond simple weight change mediate recurrence risk.
ADVICE

Prescribe Structured, Supported Exercise Post-Chemo

  • Prescribe supervised, regular exercise with professional support after chemotherapy.
  • Embed fortnightly or weekly sessions initially to build habits and social accountability.
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