
Practical AI in Healthcare S1, E12: Part 1 of 2: Dr. S. Yin Ho discusses her new book
Nov 16, 2025
Dr. S. Yin Ho, physician, entrepreneur, and author of Rushing Headlong, reflects on 25 years in health IT. She traces early electronic records, explains how design choices and billing incentives shaped today’s fragmented systems, and outlines the divide between clinical care records and research-ready data. Conversation sets up part two on generative AI.
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Episode notes
Persistent Care–Research Gap
- S. Yin Ho identifies a persistent gap between clinical care and clinical research that emerged over 25 years of health IT evolution.
- She warns that failing to document this gap risks repeating past design and policy mistakes as generative AI arrives.
Acquisition Sparked The Book
- As interim CEO of Veradigm, S. Yin Ho pushed to acquire Science.io to bridge clinical care and research with AI.
- That acquisition moment sparked her decision to take a sabbatical and write Rushing Headlong.
Generative AI Meets Flawed Infrastructure
- The book arc: build EHR infrastructure, then confront messy data, then face generative AI on top of that flawed base.
- Generative AI presumes smoother systems, but health IT's structural issues make that assumption risky.

