E57: Dr. Jessica Hekman - "The biology of a great performance dog"

Apr 6, 2018

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Summary:

Dr. Jessica Hekman is a postdoctoral associate at the Broad Institute of MIT and Harvard, where she researches how genetics affect behavior in pet and working dogs. Jessica received her Ph.D. in Animal Studies in 2017 from the University of Illinois at Urbana-Champaign, where she studied canid behavioral genetics.

Previously, Jessica graduated from the Tufts Cummings School of Veterinary Medicine in 2012, with a dual DVM/MS degree. Her Master's work was on the behavior and cortisol responses of healthy dogs to being hospitalized overnight. She also completed a shelter medicine veterinary internship at the University of Florida Maddie's Shelter Medicine Program.

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Next Episode:

To be released 4/13/2018, featuring Laura Waudby to talk about getting a happy dog in the competition ring.

TRANSCRIPTION:

Melissa Breau: This is Melissa Breau and you're listening to the Fenzi Dog Sports Podcast brought to you by the Fenzi Dog Sports Academy, an online school dedicated to providing high-quality instruction for competitive dog sports using only the most current and progressive training methods.

Today we'll be talking to Dr. Jessica Hekman.

Finally, she is also the most recent addition to the team of FDSA instructors!

Hi Jessica, welcome to the podcast!

Jessica Hekman: Thanks. I'm very excited to be here.

Melissa Breau: I'm excited to have you, and I was a little nervous reading that bio because I knew there were a lot of things in there that my tongue was not going to wrap around well.

Jessica Hekman: You did great.

Melissa Breau: I'm pretty happy with that. To start us out, do you want to tell us a little bit about your dogs and what you're working on with them?

Jessica Hekman: Yeah, I love that you start with the real easy question, because everyone likes talking about their dogs.

Melissa Breau: Of course.

Jessica Hekman: I have two dogs. I have Dashiell and Jenny. When I got Dash, I knew that I wanted to do dog sports with him. He's a 19-month-old English Shepherd, and for people who don't know that breed, they're closely related to Aussies and Border Collies, so it's sometimes a little scary how smart he is.

He's really docile, sweet, interactive, he's so much fun to work with. We've done treibball, and we've done agility, which is my favorite sport and one I've really wanted to do with him, but he has a chronic shoulder problem right now that we're in the middle of getting under control, so agility's on hold at the moment. We've also done some parkour. I think that's his favorite because he loves to jump on things, and there's still some parkour tricks that he can do, even with his shoulder issues, but a bunch that he can't. So at the moment he's in an in-person rally class with my husband. They both really like the structure of rally, even though it's not really my thing, and then with me he's doing nosework. We did that Intro To Nosework class with Stacy last session and we both really enjoyed it. Dash is the first puppy I've ever raised. I always got rescue or shelter dogs before, but I have wanted to get into studying socialization in dogs, so I wanted to actually go through it with my own dog before doing the research.

My older dog is Jenny. She's an 8-year-old mixed breed, and I know just from talking to the shelter that she came from that she definitely has some Lab in her, and we also did an ancestry test, which suggested some Samoyed, and she looks a lot like a tiny, little golden-colored Border Collie, and she sort of acts like a herding breed. She's also super-smart.

She did not get enough socialization at a young age. I got her when she was about a year old, and at the time she was terrified of all people and all new places, and she peed every time I touched her. She spent the first week huddled on a dog bed in terror, and when I needed to take her outside to pee, I would crawl backwards toward her without making eye contact, and then, without looking at her, I would have this leash, and she had a little tab permanently on a harness that she wore 24/7 exactly so I wouldn't have to touch her by the collar. So I would reach backwards without looking at her and attach the leash to her tab sort of by feel, and then we would go downstairs and outside.

After a week of this, one day I started crawling backwards towards her and she stood up and was like, "I understand the system and I can do it myself." So I took her downstairs off-leash and she went outside — safely fenced yard, so that was OK — she went outside, she came back in. So that's Jenny.

She's really scared of everything, but she's also game to work through it, and she finds her own out-of-the-box solutions to it. Most of the time that she's been with me we've just worked on her confidence levels, but they are really improving now, and since I got Dash she has also let me know that she is really interested in doing sports stuff too, so she also enjoys doing parkour, and we are doing nosework together as well. I don't think she's ever going to be able to go to a nosework trial, but that is fine with me. So those are my two dogs.

Melissa Breau: You mentioned that Dash is the first puppy that you've raised, but you knew you wanted to do agility when you got him. How did you get into dog sports? What got you started there?

Jessica Hekman: I was looking for something to do with my first dog, who was Jack, he was a Golden Retriever, so I was looking around for stuff and we started doing agility and I loved it. Jack liked it. I think he would have preferred to have done dock diving. I never found a good place to do that competitively, but we'd go to a local pond and he'd do his really impressive belly flops, so that was a good time.

We did agility together for two or three years, and we got to the point of going to trials. He cued a few times. I was very impressed with myself with him. But then I started veterinary school, and that was that for any extracurricular activities all through vet school.

As you said, I did this dual degree program, so it was extra long as well, and by the time I got out, Jack was elderly to do sports, I had Jenny at that point, and there weren't online classes, online options, and she couldn't do in-person stuff, so I was out of sports then for quite a while, through vet school and through my Ph.D., so that was about ten years, and I missed it horribly. I would watch agility on YouTube and stuff.

Jack lived to the very impressive old age of 16, which is great for a Golden Retriever. After I lost him, I got Dash, and I immediately got back into doing sports then.

Melissa Breau: What about the positive tilt of things? Have you always been a positive trainer? If not, what got you started on that journey?

Jessica Hekman: I had never trained a dog before when I got Jack. I got him in 2003. We went to what I guess you would call a balanced class for basic manners. It was not a terrible class, they didn't have us abusing the dogs or anything, but we did use some leash popping to try to get good leash manners, stuff like that. At the time I thought that was entirely appropriate. When I first learned about clicker training. I remember saying, "Oh, but there should be consequences if a dog doesn't obey you." That was where I was then.

When we started agility together, that was 100 percent positive, of course, and that was when I first learned to use clicker training myself. That was when I started shaping. At the time, though, I was still open to mild positive punishment in basic training, so I think I was gradually converted. I was going to a lot of seminars with positive trainers, I was reading books by people like McConnell and Sdeo, and eventually I started to realize, I can have a better relationship with my dogs than I do.

I've realized since then how great the approach is, not just for dogs, but for interacting with people. I use a lot less punishment in my relationships with friends and family than I used to, although I find humans can be hard to reward. You can't pop M&Ms into everyone's mouth, and you can't stop a conversation to have a friendly wrestle, so that's challenging. I'm still trying to figure that one out.

Melissa Breau: We should, as a community, decide that it's perfectly appropriate to hand out M&Ms left and right. I think that would make the world a better place.

Jessica Hekman: That would make life so much easier.

Melissa Breau: Obviously your day job now is heavily research-based. You started off in veterinary school, you started off in dog sports, how did you end up in research specifically?

Jessica Hekman: That was the long way around, for sure. I majored in medieval studies in college, and by the end of college I was already starting to feel like, you know, I really liked reading the stuff I was reading, I was reading Arthurian romances, it was great, but I was feeling like I was following paths that other people had taken before.

I had this one moment where I had some insight that I thought was fantastic, age 20, I thought I was brilliant, I took this to my advisor and he was like, "That was a great insight. It was exactly the same as this other person said 20 years ago." Basically he was saying it was so good because it was exactly the same as something someone else did, and I was like, Oh, man, I have to get out of this, and I have to do something new. I have to have some effect on the world.

I didn't go into biology then. I got into computer programming. It was the mid-'90s, we were in the middle of the dotcom boom, they were hiring warm bodies off the streets to do computer programming. That was actually a fantastic career. I was in online publishing programming for ten years. I got to the point where I was working four days a week, three of them from home, I was making a lot more money than I'm making now, and that was great. It was great for having a dog. I was at home with my dog all the time. But then I got bored. I started feeling again that I was having no real effect on the world.

The dotcom crash happened, there was a lot less money in the industry, and that meant there was a lot less interesting work going on, and right around that time I had gotten Jack, my first dog, and as a result I had also gotten into Retriever rescue. I was working with a local Retriever rescue, and because of that I started getting really interested in dog behavior. I started reading everything I could get my hands on about it, I started going on the seminar circuit, and when I read The Other End Of The Leash, by Patricia McConnell, I was like, Oh, this is it. This is what I want to do. I want to learn all about this stuff.

So I started looking into being a behaviorist, and just a quick spoiler alert — I did not actually end up being a behaviorist, but you can become a behaviorist, either with a Ph.D. or with a DVM. At the time, I knew research was the interesting thing to me, so I tried that route.

It was 2005 at this point, and there were, at that time, no labs studying dog behavior. I talked to one professor, trying to figure out what I wanted to do with my life, and he said to me, "Well, you can study wolf behavior, but Ph.D.'s don't study dogs because they're domesticated, so they're not natural animals. Vets study dogs, but they study them medically, no one studies their behavior. No one studies dog behavior."

So I was like, What do I do? I guess I could go to vet school, and I want to be able to prescribe meds in my theoretical behavior practice. So I went to vet school to become a veterinary behaviorist. At that point I had to do all my basic sciences before I could even apply. As a medievalist turned computer programmer, I had zero sciences under my belt, so I had to do all of that. It changed the way I saw the world. I had been this arty medievalist turned computer nerd, and I was like, Oh, now I'm starting to understand what goes on in bodies and brains. That was real interesting.

I got into vet school, I went to Tufts, they had this combined DVM/Master's program, as you said. I decided to do that because I thought it would give me some exposure to research. The way it works is the first two years you do the vet program, you take a year off in the middle to do the Master's, and then you go back and finish the vet program for two years.

My second year doing the veterinary program, I shadowed a veterinary behaviorist at Tufts, and that was the first time I got to, week after week, see a behaviorist in action. That was when I realized I totally did not want to do that with my life. I did not want to try to fix broken dogs. I thought it was much more effective to try to figure out why dogs break in the first place and try to stop that from happening.

Shortly after that, that was the end of my second year, and then after that I did my research year. So I spent a whole year just doing research. I still remember this one day, walking through the parking lot at Tufts on the way to my car, and thinking, Wow, I love this stuff so much. I am not looking forward to going back to vet school. It was like the skies opened and I thought, I don't have to be a behaviorist! I can go get a Ph.D. after all! It all came together. That was when I was like, I can go do research, and that will help with the prevention of behavior problems.

The research world was really changing while I was in vet school. I said that there weren't any labs doing dog stuff when I started, but while I was in vet school, people started to realize that, in fact, dogs are totally fascinating models for research. They are natural animals, and the fact that they've evolved to live inside civilization along with humans — that makes them more interesting, not less interesting.

So after I finished vet school, I did do an internship, but then I did a Ph.D. at the University of Illinois at Urbana-Champaign, working with Kukekova Lab, and that lab was actually founded just the year before I came there. I was one of her first two grad students. So it's very much been a process of when I'm ready to take my next step, things have appeared just barely in time for me to get there. In that lab we studied tame foxes, not dogs, but the tame foxes are a fantastic model for dogs and for domestication. It was a really great opportunity for me. I learned a lot.

But I really wanted to get into studying the genetics of pet dogs, and again, while I was in that program, a few people were starting to do that. No one had quite figured out how to do it at a large scale, so when you're working not with lab animals but with pets, and there's so much variety in their genetics and in how they're raised, you need really, really large numbers of them, and that was really hard for anyone to figure out how to do.

But just a couple of years before I was ready to graduate, again, this new lab sprang up, they were doing exactly that, so that's where I am now, Karlsson Lab at the Broad Institute. It's spelled Broad but it's pronounced Brode, just to be super-tricky for people. I like to say of Karlsson Lab that it's, like, thank God they're doing exactly what I thought I would have to do, so I don't have to organize this massive citizen science approach to studying pet dogs, because my new boss, Elinor, has already done that, and I can just focus on the fun parts. So that's my crazy journey. It's probably a longer answer than you were looking for.

Melissa Breau: No, it's interesting. You've had a lot of interesting experiences and steps along the way. I'd love to dig a little more into what you're doing now. Do you mind sharing a general overview?

Jessica Hekman: Sure. Karlsson Lab, where I am now, takes what we call a citizen science approach to studying pet dogs. What we do is we collect a lot of dog behavior information and DNA directly from dog owners, and we use that to try to find connections between differences in the dog's DNA and their different behavioral traits.

The main project that has started out collecting that is called Darwin's Dogs, and you can go to DarwinsDogs.org and participate, and I'm sure that all of you will do that, and you should definitely do that. Right now we're very much in the data collection phase, so at the moment I'm doing a lot of what turns out to be basically project management, making sure that all the stuff is coming together, that we're storing the data in a reasonable way, things like that. But I am already getting to do some data analysis. I actually, really excitingly just last week, I got my hands on about 15 years worth of pedigree and behavioral data from a school that breeds guide dogs. I'm getting to analyze that in order to write a paper about it. As the data is coming in from other projects, the plan is that I'll be one of the ones to analyze that as well.

Melissa Breau: That's awesome. I know we've chatted a bit about having your boss on the podcast, too, to talk more about some of this stuff, but I'd love if you want to share just a couple of the projects you guys are working on. You mentioned DarwinsDogs.org, so I'll make sure that there's a link to that in the show notes for folks. Do you want to share any other stuff that listeners might be interested in?

Jessica Hekman: For sure. We actually have a brand new project that's about to launch that FDSA folks can participate in, and it's actually, even if you don't have a dog, although I know that pretty much everyone listening to this will have a dog. In my nosework class that I did with FDSA, I was Bronze in the introductory nosework and one person was at Gold with a cat, which was fantastic.

Melissa Breau: That's very cool.

Jessica Hekman: Yeah, that was neat. This new project is called Muttmix. That's at muttmix.org. The idea is that we will show you photos of a whole bunch of mixed-breed dogs, and you get to guess what is in their breed mix. We will collect guesses from a whole bunch of people, and then we will e-mail you back afterwards and tell you what was in those dogs, based on their genetic analyses that we did. So it should be a lot of fun for you. And then the data that we collect will be used to help us analyze how good people are at looking at a dog and telling exactly what breed is in there, which, just a spoiler alert, it's really hard to do that by looking.

It turns out that mutts are really, really interesting, and very few people, if any, have really surveyed them. Most of the papers out there on dogs, particularly genetic papers, are about purebred dogs. So muttmix.org, and it's starting in a few weeks, but if you go right now, you can give your e-mail address and then we can let you know when it goes live. That's Muttmix.

And then the main project that I personally am working on is called the Working Dog Project, and that is, we collect behavioral and genetic information from working dogs to find out the genetic influences that make dogs more or less good at their job, or more or less able to succeed in training programs. For example, a guide dog school typically only has about half of the puppies that they train succeed at becoming guide dogs. Why is that? Is there anything we can do to help them do better?

And, by the way, if it occurs to you that sports dogs are a lot like working dogs, that has also occurred to me, and I am totally planning to expand this project to include sports dogs, so stay tuned about that. And if and when that happens, I will definitely be letting FDSA folks know.

Melissa Breau: Awesome. I look forward to that, and I can't wait to see what some of the outcomes are of the research you're working on. It all sounds so interesting.

Jessica Hekman: Us too. It's sad that research is so slow, because we would really like the answers yesterday.

Melissa Breau: Fair enough. I know that, talking about research, you did include a bunch of that in the webinar you just did, kind of the other end of things, on the biology of socialization, and you've got another coming up on April 12 on epigenetics. Do you want to explain what epigenetics is, and then share a little bit on what the webinar will focus on?

Jessica Hekman: Epigenetics is a way that organisms, including dogs, record the experiences that they've had in their DNA. We used to think that the DNA sequence is something that never changes for a particular individual. It turns out, though, that epigenetics is this mechanism that this cell has. It's like marks that you put on the DNA, so the sequence itself doesn't change, but there's these marks that are added on it, sort of like a bookmark in a book, so that the content of the book doesn't change, but you can put a bookmark in it to save a really important page that you want to come back to again and again.

Animals can do this with their DNA to say, "This is a bit that is really useful for the environment that I live in, and I want to use this bit a whole lot." So this is a new way that we look at what makes up an animal's personality — not just their genetics, but

also this way that animals have of recording their experiences in their DNA.

In this webinar I'll talk about what we know about epigenetics, and I will specifically relate it to dogs. A lot of the epigenetics resources that are out there for people to read are obviously very human-oriented, and so I will focus very much on "What does this mean for your sports dog?"

Melissa Breau: Kind of to take that and ask what is probably a way-too-broad question, what does go into a perfect performance dog from that standpoint?

Jessica Hekman: Lots of things. There's very complex effects on a lot of different genes interacting with each other in ways that are really hard to predict, but that's what my job is, is to try to find ways of predicting how that's going to work.

And then equally complex there's the effects of the dog's environment, of course. But the environment — we don't always think of it as it actually starts at conception in the uterus, with the hormones that the mom passes on to the puppies in nutrition, and then the environment also includes the time in the nest with their littermates, how the puppy is socialized, how the dog is trained. We can only control a tiny portion of all of this, like some of the socialization and the training, and I knew that theoretically when I got Dash as a puppy, but I have to admit I still figured I'd be able to control a bit more of him than I could in the end. So yeah, perfect performance dog.

Melissa Breau: Are there common misconceptions that dog sports people tend to have about this sciencey stuff? If so, what can you do to set the record straight?

Jessica Hekman: I think that a lot of people have this hope that science, and particularly genetics, will be able to give us black-and-white answers to questions that we have, that maybe a dog who has behavioral issues, or issues in the ring, has some underlying genetic problem that can't be changed and that perhaps could be identified in a test, that we'll maybe discover one gene for aggression and be able to breed it out.

Of course, in real life, biology is incredibly complex and there's no black-and-white, there's really just shades of gray. But of course that doesn't mean that there isn't a lot to learn and understand about how the body and brain work that can be really enlightening when we're thinking about how to interact with our dogs. I hope that answers that question.

Melissa Breau: That's actually an interesting way of thinking about it, and I think it's important to note that even science doesn't have all the answers. It's a complex topic, and to a certain extent you do need to wade in waist-deep to get a good understanding of all the bits and pieces. What do you think about for the future? Where do you think the future of some of this stuff will lead us, and what subjects are there out there that you hope that science can find the answers to?

Jessica Hekman: Personally, I'm really hoping we're going to find ways of improving how we breed dogs. There are genomic technologies that can be useful to help the process of selecting dogs to breed in order to produce puppies with the traits that we want, and in fact this is done as a matter of course in the cattle industry. The technology is there. It's made a massive difference in the ability of the cattle industry to select for traits like milk production.

What we need to make it happen for dogs is just for the community to get together and to pool genetic and behavioral data. The data that Karlsson Lab, where I work now, is collecting could be used for exactly this kind of thing.

But the hard part, I think, will be not so much the science, but will be agreeing on what everybody is breeding for. It's the intersection of science and society where stuff gets interesting. How do you work together to breed for things like health and solid personalities instead of things like fancier coat colors and flatter faces? That's really going to be the big struggle, but that's where I hope to see the dog community going.

Melissa Breau: I guess part of me peripherally knew that the cattle industry had been breeding for things like increased milk production, but you don't really think about it as a concerted effort, as, like, the industry sat down and looked at it from a scientific perspective. You think, Oh, they did it the same way we do it in dogs, where it's just two that have a line, or have a history, and let's just keep going down that thread. So it's interesting.

Jessica Hekman: They're massively well organized, and it's kind of scary if you look at the statistics. The output of milk from an individual cow since 1950, it has more than tripled in individual cows from 1950 to today. One of the things that the cattle industry has going for them is USDA. They have this federal agency that is paid to organize them. We don't have anything like that, and trying to imagine organizing dog breeders to work together is kind of crazy.

Melissa Breau: Fair enough, yes.

Jessica Hekman: Imagine talking to one person who has their lovingly curated and selected line of dogs, and saying, "OK, for the good of the whole breed, we think you shouldn't breed this particular dog anymore." Not going to happen. So it's a really interesting difference between the two groups.

Melissa Breau: Fascinating. It's such an interesting concept to think through and think about. To shift gears a little bit, in addition to your webinar, you're doing a class on some of this stuff in June. I wanted to ask you to share a little about the class and maybe help folks decide whether or not the class would be a good fit for them.

Jessica Hekman: I'm really looking forward to it. It's going to be BH510 it's called The Biology of Building a Great Performance Dog. It's going to be basically about the biology underlying dog development, like what makes each dog her own individual self.

A lot of what I'll talk about has to do with genetics and very early socialization, so the class will be particularly useful, I think, for people who want to think through how to find their next dog, what to look for in choosing a breed and a breeder, or in choosing a shelter dog or a rescue dog. But we'll also talk about decisions on things like spay/neuter, whether to do it, when to do it, so that could be useful for people with puppies or even people with young adult dogs.

And then I also think it should really appeal to anyone who wants to get their science geek on about dogs, like what makes up a dog's personality. So even if you're not thinking about getting another dog, just if you want to learn some genetics and some biology from a dog perspective, and a think through what's going on in their brains, what's going on in their bodies that makes them act the way they do, it ought to be a great class for you.

Melissa Breau: Since it's your first time on, I do have three questions I always try to ask each time somebody comes on for the first time. I want to round things out with those. To start us off, what's the dog-related accomplishment that you're proudest of?

Jessica Hekman: Oh, Jenny, for sure Jenny. When I got her, as I said, she peed whenever I touched her, and now I can actually bring a stranger into the house. She still gets nervous and shakes, but as soon as the stranger tosses her a treat, she flips over into, like, Oh, a treat game, and she stops shaking, her ears come up, she starts making cute faces at the stranger to get more treats.

Very occasionally, if someone really is good with dogs, Jenny will let them pet her, even though she's just met them that day, which I never would have believed a few years back would ever have happened.

She can go out in public, she can go walking on leash around the neighborhood, she can go off leash in a safe park. So we've made some amazing progress together. Sometimes I can't believe she's come so far.

You asked for my proudest accomplishment, and I feel like she's really been working hard on that too, but the two of us together I think have made some fantastic progress.

Melissa Breau: I absolutely think that counts. I don't think she could have done it without you. What's the best piece of training advice that you've ever heard?

Jessica Hekman: It's only in the last couple of years I heard this, I think from Jean Donaldson. She said, "Most people don't use enough treats," which I love. It's simple, it's concise, it's totally useful. Use more treats. It's easy, and it's so helpful in getting us out of the mindset of thinking, The dog should do this because I asked her to, and into the mindset of, How can I make this more fun for the dog?

Melissa Breau: Right, right. That's fantastic, and I think we hear similar things in a lot of different places, but I do like it in that concise, easy to digest. For our last question, who is somebody else in the dog world that you look up to?

Jessica Hekman: Can I have more than one?

Melissa Breau: Yes, absolutely.

Jessica Hekman: OK. The obvious answer, I guess, would be Denise, because in addition to her stellar dog handling skills, she also has stellar human handling skills. She's so great at helping people learn while making them feel good about themselves, and that's really hard to do — not just be good at dogs, but be good at people.

I already mentioned Patricia McConnell, whose books are the reason I chose my new career. She had insights into the fact that dog minds are really fascinating in their own right, and I will always be indebted to her for that.

And finally, he's not exactly in the dog world, but my science hero is Dr. Robert Sapolsky. He learned some amazing things about how the stress response works. He's a fantastic lecturer, and a lot of his talks are on YouTube and I highly recommend checking them out, if you're interested in how the brain functions and how stress affects behavior. He does not talk about dogs specifically, but his material is totally relevant to them and to training. So Sapolsky. Highly recommended.

Melissa Breau: Excellent. I will try to find a YouTube video or two that we can link to in the show notes for everybody.

Jessica Hekman: Let me know. I can find you one.

Melissa Breau: Absolutely. That would be great. Thank you so much for coming on the podcast, Jessica. I'm thrilled that we got to chat. This was a lot of fun.

Jessica Hekman: Oh, thanks. I had a fantastic time.

Melissa Breau: And thank you to all of our listeners for tuning in!

We'll be back next week with Laura Waudby to talk about training for a happy dog in the competition ring.

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Credits:

Today's show is brought to you by the Fenzi Dog Sports Academy. Special thanks to Denise Fenzi for supporting this podcast. Music provided royalty-free by BenSound.com; the track featured here is called "Buddy." Audio editing provided by Chris Lang.