Joe Rogan Experience Review podcast 521 JRE Review of Duncan Trussell
Apr 14, 2026
A wild conversation bouncing from superintelligent AI and local model risks to bizarre military and underwater craft claims. They riff on UFO footage, viral clips, and whether angels were aliens. Psychedelic tales include ketamine, ibogaine, and strange long-term effects. Politics and propaganda come up often, with talk of Trump, Iran, media influence, and how information shapes public belief.
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Duncan's Ketamine Addiction And Long-Term Damage
- Duncan revealed he struggled with daily ketamine use for about a year and experienced addiction-related harms.
- Adam and Pete describe extreme effects like K-holes and the long-term Bristol bladder damage requiring surgery.
Ibogaine As A Hard Reset For Addiction
- Ibogaine is presented as a one-off psychedelic treatment that can dramatically reduce addiction and PTSD.
- Pete and Adam note it's intense, often uncomfortable, and rarely used recreationally because of the difficult experience.
Local AI Models Fuel An Edgier Space Race
- Local AI models let users run powerful assistants on their own machines without cloud restrictions.
- Adam explains Olama-style models store gigs of data locally and can be modified to remove safeguards, driving a race for edgier AIs.