NEI Podcast E245 - The Best of the PsychopharmaStahlogy Show
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Jan 1, 2025 
Join Stephen Stahl, a prominent psychopharmacology expert, and David Goodman, an ADHD specialist, as they discuss the complexities of diagnosing ADHD in women. They highlight societal biases and the role of hormonal changes in managing the condition. Michael Cummings shares insights on navigating treatment-resistant psychosis, emphasizing the use of clozapine for improved outcomes. James Knoll delves into antisocial personality disorder, exploring its origins and gender differences, while addressing the societal perceptions surrounding these disorders.
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ADHD Recognition
- ADHD in children has a higher recognized ratio in boys than girls (3:1), while it approaches 1:1 in adulthood.
- This suggests an issue with recognition, not prevalence, influenced by how symptoms present and who refers patients.
Lithium and Dementia
- Lithium's neuroprotective effects can reduce future dementia risk by 49% in older individuals when taken long-term at therapeutic doses.
- Valproate, another mood stabilizer, showed no such effect in the same study.
Lithium in Older Adults
- Avoid reflexively discontinuing lithium in older patients solely due to age.
- Base discontinuation decisions on GFR, considering medical context and potential comorbidities.