Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 535 Masterclass: Inflammation, Hormones & Weight Loss | Hormones & Menopause

Dec 31, 2025
This conversation features Dr. Mary Claire Haver, an expert in midlife women's health, Dr. Rocio Salas-Whalen, who specializes in obesity medicine, and Physician Assistant McCall McPherson, focusing on thyroid care. They delve into how inflammation affects weight gain and share strategies like macronutrient timing and strength training. The benefits of GLP-1 drugs for appetite control and muscle preservation are discussed, along with essential labs to monitor metabolic health. Prioritizing self-care and adapting nutrition is also emphasized for long-term wellness.
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ADVICE

Prioritize Strength Training

  • Replace long cardio sessions with regular strength training to build and preserve muscle mass and improve metabolism.
  • Increase dietary protein to naturally reduce cravings and support body composition changes.
INSIGHT

How GLP‑1s Alter Appetite Biology

  • GLP‑1 agonists mimic endogenous hormones but are long‑acting and resist rapid degradation.
  • They act on satiety and reward pathways to reduce hunger and blunt food‑related reward signals.
ANECDOTE

Emotional Relief From GLP‑1 Treatment

  • A patient cried in Dr. Salas‑Whalen's office because for the first time they stopped obsessing about food and weight.
  • The medication freed mental space and improved quality of life after decades of preoccupation.
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