Everything we know about the "promising" Coronavirus vaccine, and when will Biden call Boris?

Experts are hailing “promising” news of a Covid-19 vaccine that trials show to be 90 per cent effective. Its makers, Pfizer and BioNTech are calling it a "great day for science and humanity" but, if it really does work, when could the general population get to see it? We speak to Professor Karol Sikora, a former director of the World Health Organisation's cancer programme, who tells us how the vaccine works, and reveals how difficult it will be to roll it out internationally. 

Also, our political editor Joe Murphy has been talking to Downing Street sources about when they think President-elect Joe Biden will give Boris Johnson a phone call. There has been speculation that the Prime Minister may have to wait in turn behind European Union leaders, including German Chancellor Angela Merkel and French President Emmanuel Macron. Joe Biden has branded Brexit laws on the internal market as a threat to peace in Northern Ireland, but UK officials insist the two leaders agree on many issues including climate change.

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