Becker’s Healthcare Podcast

Scaling AI in Healthcare with Governance, Trust, and Impact at City of Hope

Mar 21, 2026
Nassim Eftekhari, Chief AI and Analytics Officer specializing in machine learning for patient care and research. Simon Nazarian, Chief Digital and Technology Officer leading enterprise digital platforms. They talk about building AI infrastructure and governance. They explore agent orchestration and AI literacy. They discuss change management, blended intelligence, and expanding patient access with technology.
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INSIGHT

Governance As An Enabler Not A Gatekeeper

  • City of Hope reframed AI governance as an enabler to scale responsibly rather than a policing barrier.
  • Simon built clear decision rights and moved governance closer to clinical teams to support durable, system-wide adoption.
ADVICE

Orchestrate Agents To Avoid Fragmentation

  • Orchestrate AI tools and agents centrally so they interoperate instead of multiplying isolated point solutions.
  • Nassim warned against letting “tens, hundreds, thousands of agents” run independently and creating new bottlenecks.
INSIGHT

Scale Requires Distributed Responsibility

  • Scaling distributed agency requires rethinking decision rights and organizational design.
  • Simon calls innovation federated and stresses distributed responsibility rather than centralized permissioning.
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