The Joe Rogan Experience #1349 - David Sinclair
Sep 10, 2019
David Sinclair, a Harvard geneticist and author of "Lifespan: Why We Age And Why We Don't Have To," dives into groundbreaking research on aging and longevity. He discusses innovative measures like the Horvath clock for determining biological age. The conversation includes fitness strategies for busy lifestyles, the intersection of wellness and nature, and intriguing survival stories. Sinclair also covers CRISPR technology's potential and examines societal perceptions of aging, advocating for personal health choices and the importance of mental engagement.
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Pulsing Exercise and Metformin
- Pulse exercise and recovery, don't do everything every day.
- On exercising days, David Sinclair avoids metformin to allow his body to recover.
Metformin's Impact on Exercise
- Metformin may hinder the mitochondrial benefits of exercise.
- It interferes with the energy production needed for mitochondrial amplification after exercise.
Smart People, Dumb Habits
- Joe Rogan points out that David Sinclair only works out one day a week for three hours.
- He criticizes smart people with unhealthy habits, citing Peter Hotez's poor diet.
