Energized with Dr. Mariza

734: The Truth About Botox, Sunscreen & Skin Aging After 40: What Actually Works (and What’s a Waste) with Dr. Mamina Turegano

Apr 2, 2026
Dr. Mamina Turegano, a triple board-certified dermatologist who blends medical and integrative skin care, breaks down midlife skin shifts. She covers hormonal effects in perimenopause and topical estradiol, simple daily routines with sunscreen and retinoids, realistic use of Botox, and lifestyle steps that influence skin aging.
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INSIGHT

Estrogen Is The Major Driver Of Midlife Skin Change

  • Estrogen strongly drives skin structure by supporting collagen, hyaluronic acid production, and epidermal thickness, so declines accelerate wrinkles, dryness, and crepey skin.
  • Dr. Mamina Turegano cites a 20–30% collagen drop around menopause and reduced hyaluronic acid as key mechanisms.
ADVICE

Simple Foundational Routine That Actually Works

  • Keep a minimal, effective routine: cleanse daily, moisturize to support the skin barrier, wear sunscreen each morning, add vitamin C in AM and a retinoid at night.
  • Use moisturizer after retinoids and choose retinoid strength based on tolerance and dryness risk in postmenopause.
ADVICE

When To Reapply Sunscreen

  • Reapply sunscreen mainly when outdoors or exercising; a single morning application is impactful for mostly indoor days.
  • Use sticks, sprays, or powders for quick on-the-go reapplication over makeup when needed.
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