MCAT Basics (from MedSchoolCoach)

Acids and Bases

Sep 2, 2025
Dive into the fascinating world of acids and bases, where foundational chemistry meets biology. Discover the role of indicators in titrations and the critical nature of buffers in keeping our body's pH in check. Learn how to calculate pH, differentiate between strong and weak acids, and utilize ICE tables for problem-solving. The podcast also explores the blood buffer system's function in homeostasis and offers essential strategies for mastering these concepts for the MCAT.
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INSIGHT

Strong vs Weak: Know The Six Strong Acids

  • Strong acids/bases fully dissociate while weak ones establish equilibria described by Ka or Kb.
  • Memorize the six strong acids (HI, HBr, HCl, HClO4, H2SO4, HNO3) for quick MCAT work.
ADVICE

Calculate pH From Stoichiometry

  • For strong acids, compute [H+] from stoichiometry then pH = -log[H+].
  • Remember pH can be negative with very concentrated acids.
ADVICE

Use ICE Tables For Weak Species

  • For weak acids/bases use ICE tables with the given Ka or Kb to solve for x and then compute pH.
  • Plug the solved [H+] or [OH-] into -log to get pH or pOH.
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