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Leaky Gut Expert: This Gut Mistake Leads To Cancer. The Cheap Spice That Helps Repair A Damaged Gut!

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Jan 1, 2026

Guest

Will Bulsiewicz

Dr. Will Bulsiewicz, a leading gastroenterologist and the US Medical Director at ZOE, dives into the critical connection between gut health and overall wellness. He reveals how leaky gut can trigger inflammation and chronic diseases, including cancer. The discussion highlights the power of fiber and fermented foods in restoring microbiome health. Will also shares insights on the gut-brain axis, constipation as a key bloating factor, and lifestyle changes that promote a healthier gut. Plus, he addresses the truth about fecal transplants and common misconceptions about gluten intolerance.

02:11:48

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Episode notes

Microbiome Influences Cancer Immunotherapy

The microbiome affects cancer treatment outcomes by modulating immune responses.
Antibiotics before immunotherapy worsen outcomes, while fecal transplants from responders can double effectiveness in melanoma.

Glyphosate May Affect Wheat Tolerance

Glyphosate residues on conventionally dried wheat may disrupt gut microbes.
People often tolerate European wheat better because it is less likely to be sprayed with glyphosate.

Try Sourdough Or Organic Wheat First

If wheat bothers you, try fermented sourdough or organic options to reduce fructans and glyphosate exposure.
Consider testing for fructan sensitivity rather than assuming gluten intolerance.

Get the Snipd Podcast app to discover more snips from this episode

Why inflammation matters and its gut connection

02:00 • 3min

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How gut barrier breakdown causes inflammation

Microbiome's role repairing the gut barrier

07:20 • 4min

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Causes of chronic gut damage and inflammation

11:27 • 2min

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Fecal transplants: what they are and when used

13:52 • 3min

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Microbiome influence on cancer and immunotherapy

16:26 • 3min

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Parkinson's and the gut-brain connection

19:23 • 2min

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Should you get a fecal transplant yourself?

21:41 • 39sec

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Scope of common gut problems and personalization

22:20 • 2min

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When symptoms warrant concern

24:41 • 50sec

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Constipation as a primary driver of bloating

25:30 • 2min

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Why gas occurs and microbiome's role

27:34 • 2min

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Diet, microbiome and common triggers

29:50 • 3min

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Fructans often mislabelled as gluten intolerance

33:17 • 6min

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Timeline to repair the gut depends on damage

39:17 • 4min

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Inflammatory bowel disease origins and microbiome role

42:53 • 45sec

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Antibiotics greatly increase bowel disease risk

43:38 • 56sec

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Clinical fecal transplant success story

44:34 • 4min

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Diet trends: extremes vs whole-food balance

48:47 • 4min

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Fiber-maxing trend and how to increase fiber safely

52:54 • 3min

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Why fiber and short-chain fatty acids matter

55:56 • 5min

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Lifestyle factors, tribal populations and ageing

01:01:01 • 11sec

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Alcohol causes leaky gut and inflammation

01:01:12 • 7min

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Turmeric (curcumin) reduces cytokine signaling

01:08:24 • 2min

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Will's perfect gut day: circadian and meals

01:10:35 • 10min

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Breakfast choices and supplements timing

01:20:53 • 7min

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Lunch, social connection and afternoon walk benefits

01:28:12 • 6min

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Best time to exercise and meal spacing

01:34:17 • 4min

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Evening routine, sleep and supplements

01:38:19 • 2min

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Benefits of time-restricted eating and consistency

01:40:20 • 5min

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Trauma's profound impact on gut function

01:45:25 • 5min

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Healing trauma to improve gut health

01:50:47 • 53sec

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Bristol stool chart and bowel health

01:51:40 • 3min

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Constipation solutions: fiber plus magnesium

01:54:53 • 1min

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Four missing diet elements that transform gut health

01:56:09 • 4min

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Fermented foods increase diversity and lower inflammation

• Mentioned in 22 episodes

Plant Powered Plus

William Bulsiewicz

Tired of your health issues? Top gastroenterologist DR WILL BULSIEWICZ reveals NEW information about how leaky gut drives inflammation, cancer risk, bloating and brain fog, and the daily habits to heal FAST.

Dr Will Bulsiewicz is one of the world’s leading experts on the gut microbiome. He is the US Medical Director at ZOE, founding director of The Gut & Microbiome Center for Excellence and bestselling author of “Fibre Fuelled” and the upcoming book, “Plant Powered Plus”.

He explains:

◼️Why inflammation is driven by the gut, not just genetics

◼️How leaky gut triggers bloating and immune dysfunction

◼️The gut-immune link behind cancer and chronic disease

◼️Why fermented foods and fibre rebuild the microbiome

◼️How the gut-brain connection shapes mood, focus, and longevity

(00:00) Intro

(03:28) What Is Inflammation?

(05:36) Can You Be Thin and Still Have Inflammation?

(06:11) Why Does Chronic Inflammation Happen?

(07:11) The Shocking Link Between Inflammation and Gut Health

(10:47) Chronic Inflammation Causes These Diseases

(12:17) The Importance of a Healthy Gut

(12:52) Faecal Transplants to Heal the Gut

(15:26) Link Between Gut Microbiome and Cancer

(18:19) Parkinson's Could Start in the Gut

(20:40) Can Anyone Get a Faecal Transplant?

(21:22) A Lot of Us Have Gut Issues

(23:37) Does Gas and Bloating Indicate a Health Issue?

(31:34) Everyone Thinks They're Gluten Intolerant

(32:36) Processing Issues With Gluten

(35:04) Is Sourdough the Best Bread?

(36:13) Your Gluten Intolerance Might Be This Instead

(38:18) How Long Does It Take to Repair the Gut?

(41:17) What Causes Bowel Diseases?

(42:42) Antibiotics Double Your Risk of Bowel Disease

(43:16) Fixing a Chronic Gut Issue With a Fecal Transplant

(47:46) What Diet Trends Spread Misinformation?

(51:54) Fibremaxxing and the Importance of Fibre

(54:48) Best Foods to Eat for Fibre

(59:11) How Fibre Affects Immunity and Ageing

(1:00:00) This Is What Alcohol Does to the Gut

(1:05:34) Ads

(1:07:24) Benefits of Turmeric

(1:09:22) Dr Will's Perfect Gut Day

(1:19:40) Good Breakfast for Children

(1:20:44) What Would Impact Your Child's Gut Health?

(1:25:22) Dr Will's Perfect Gut Day

(1:33:19) Optimal Time to Workout

(1:34:56) Perfect Time Between Meals

(1:35:54) Perfect Evening Routine

(1:39:23) Would You Recommend Fasting?

(1:42:21) Ads

(1:44:18) Trauma Impacts Gut Function

(1:49:35) How Would I Heal My Trauma-Related Gut Issues?

(1:50:42) Stool Test – Is Your Gut Healthy?

(1:53:33) Magnesium for Constipation and Sleep

(1:55:03) This Is Easier Than You Think – 4 Things You Need

(1:58:58) Dr Will's Transformation

(2:05:02) Message to My Dad

(2:09:34) Your Biggest Regret

Follow Dr Will:

Instagram - https://bit.ly/457iRAx

The Gut Health MD - https://bit.ly/4p2svLU

Youtube - https://bit.ly/4aGQJrK

Dr Will Bulsiewicz’s upcoming book, ‘Plant Powered Plus: Activate the Power of Your Gut to Tame Inflammation and Reclaim Your Health’:

UK Version: https://amzn.to/45hIcb1
US Version: https://bit.ly/49hpCAZ

Independent Research: https://docs.google.com/document/d/1YDjg-o8aGLb-Okn6xk3L06SclNtjybYl8pejVf12f2A/edit?pli=1&tab=t.0

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