Breakpoints #85 – Who You Gonna Call? Mythbusters! Antibiotic Myths for Infectious Diseases Clinicians
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Sep 15, 2023 Dr. Jason Gallagher, an infectious disease pharmacist, and Dr. Melissa Johnson, an expert in infectious disease pharmacy, join Dr. Erin McCreary to debunk widespread antibiotic myths. They explore how social media sparked vital discussions among clinicians and review eight common misconceptions regarding antibiotic efficacy. Critical flaws in past testing are revealed, alongside the importance of evidence-based practices. They also tackle physician hesitance in prescribing effective treatments and discuss the reevaluation of guidelines for endocarditis, all while making the topic engaging and accessible.
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Leadership and Data Drive Change
- Engage hospital leadership and clinical teams to support stewardship goals.
- Regularly share actionable data feedback to empower clinicians in changing antibiotic use.
Lab Flaw Masks Bactrim Activity
- The myth that trimethoprim-sulfamethoxazole (Bactrim) is inactive against group A strep stems from lab testing flaws.
- Thymidine in testing media falsely reduces apparent activity, misleading clinical perceptions.
TMP-SMX Useful for Cellulitis
- TMP-SMX monotherapy is probably appropriate for cellulitis when beta-lactam use is contraindicated.
- Clinical data shows patients with streptococcal cellulitis do well on TMP-SMX alone.