
Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast Episode 316: Keywords Part 31: Airway Anatomy and Pharmacology with Tym Kajstura
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Sep 7, 2025 Dr. Tym Kajstura, a Doctor of Anesthesiology, returns to discuss vital concepts in airway anatomy and pharmacology. He dives into the structure and function of the respiratory system, spotlighting the complexities of laryngeal innervation and its clinical implications. The conversation highlights the importance of anatomical knowledge for intubation and explores how innovations in medical products are enhancing patient care. Practical applications and insights into respiratory mechanics make this a must-listen for anyone in the field.
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Diaphragm Does Most of Inspiration
- Diaphragm provides ~75% of inspiratory volume while external intercostals contribute most of the rest.
- Expiration is passive at rest but uses internal intercostals and abdominal muscles during increased effort.
Key Pediatric Airway Differences
- Infant airways differ: larger occiput, larger tongue, higher larynx (C2–C3), omega-shaped epiglottis, softer cartilage, and relatively smaller lower airways.
- Tests often state infant narrowest point is subglottic, though recent data question this.
Calculate Dead Space As 2 mL/kg IBW
- Estimate anatomic dead space as 2 mL/kg of ideal body weight when height is unknown.
- Use gender and height to calculate ideal body weight when provided for accuracy.

