Redefining Medicine Implementing Stem Cell Support Strategies in Real World Care | Greg Kelly, ND
Mar 10, 2026
Greg Kelly, naturopathic physician and longevity product leader, outlines a practical, cyclical approach to cellular rejuvenation. He compares senescent cells to yellow leaves that need periodic pruning. He explains why clearing inflammatory cells first improves stem cell support and describes a simple monthly rhythm of short senolytic pulses followed by stem cell support.
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Senescent Cells Create A Systemic Inflammatory Stew
- Senescent cells secrete a harmful inflammatory stew called SAS factors that stress surrounding cells and drive systemic aging.
- Animal studies showed oral senolytics remove these cells, reduce inflammation, and restore youthful resilience in frailty and muscle function.
Dr Kahn Always Prunes Before Injecting Stem Cells
- Dr. Kahn routinely gives senolytics before stem cell injections to improve the tissue milieu and increase injected stem cell effectiveness.
- Kelly learned this from interviewing Dr. Kahn, who noted it as standard practice in his clinics.
Four Doors Model Explains When To Use NAD Senolytics And Stem Cells
- Greg Kelly frames cellular stress as four doors: hormesis, repair, senescence, and cell death, explaining intervention points.
- NAD supports door one resilience; senolytics clear door three senescent cells; stem cell support aids subsequent repair and rejuvenation.