Future Tense

Ancient viruses, new threats

Nov 20, 2025
Dr. Jean-Michel Claverie, an expert on ancient viruses, discusses how thawing permafrost could release dangerous pathogens, detailing the revival process in the lab. Dr. Christine Pratt explains her work at the European Virus Archive, emphasizing the need for global cooperation in pandemic preparedness. Meanwhile, Dr. Aaron Bernstein connects climate change to emerging infectious diseases, highlighting how habitat shifts increase spillover risks. Together, they stress the urgency of proactive measures to prevent future pandemics and the pivotal role of decentralized archives.
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INSIGHT

Permafrost Hides Massive Viral Diversity

  • Metagenomics reveals a vast unseen diversity of ancient viral sequences in permafrost beyond what lab revival shows.
  • Claverie warns our experiments sample only a tiny fraction of that ancient viral diversity.
ADVICE

Reduce Arctic Exposure To Thawing Sites

  • Limit human and animal exposure in thawing Arctic regions to reduce risk from released pathogens.
  • Target industrial activity and ensure biosafety measures where permafrost is melting and people gather.
ANECDOTE

Using Amoeba Viruses As Safe Probes

  • Claverie uses amoeba-infecting viruses as safe probes to explore ancient viral threats.
  • He expresses concern about other groups attempting to revive mammoth-killing viruses due to cross-species risk.
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