
Armchair Expert with Dax Shepard Kathryn Paige Harden (behavioral geneticist)
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Mar 18, 2026 Kathryn Paige Harden, behavioral geneticist and author who studies how genes shape behavior. She explores why we do things we regret. Short takes on original sin, genetic predictors of misdemeanor versus felony behavior, prenatal roots of risk, and how societies can balance accountability with compassion.
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Original Sin Shapes How We Think About Blame
- Augustine's doctrine of original sin frames human tendencies as inherited liabilities, shaping modern intuitions about blame and morality.
- Harden ties Romans' line "the things I don't want to do, I keep on doing" to scientific questions about why humans act against their own intentions.
Travis's Bad Trip Turned Into a Moral Thought Experiment
- Kathryn recounts Travis's terrifying bad LSD trip where he believed he had killed her, which felt like a visceral enactment of original sin.
- The episode became central to her book because it revealed how utterly convinced someone can be of inescapable guilt.
Don't Do Psychedelics Without Integration Support
- Use psychedelic experiences only with trusted people and integration support to process extreme episodes safely.
- Harden notes Travis recovered partly because he talked through the trip with friends, family, and a therapist afterward.







