
The AI Policy Podcast Andreessen Horowitz's Jai Ramaswamy, Matt Perault: AI Regulation & Innovation
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Mar 3, 2026 Matt Perault, head of AI policy at Andreessen Horowitz, former Meta and academic technopolicy leader. Jai Ramaswamy, Chief Legal and Policy Officer, ex-federal prosecutor and compliance executive. They discuss why venture capital moved into policy, state versus federal roles in AI regulation, risks around open source and national competitiveness, and practical state-level solutions for mental health and worker support.
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Policy Work Builds Industry Infrastructure Not Individual Lobbying
- A16Z positions its policy work to build industry-wide technical and regulatory infrastructure rather than act as an outsourced government affairs shop for each startup.
- The firm helps startups 'fish for themselves' by providing tools and frameworks that support many companies across 10–15 year timelines.
American Dynamism Portfolio Brings Founders To National Problems
- A16Z's American Dynamism portfolio targets founders solving national interest problems across defense, space, supply chain, law enforcement, and education.
- The portfolio surfaces companies that bring Silicon Valley innovation into long-neglected public-sector domains.
Provide Clear Stable Rules For Startups
- Favor regulatory certainty and stability so startups can plan across 10–15 year investment horizons.
- Avoid vague, enforcement-first rules that leave founders unsure whether their activities are legal during early scaling.


