
New Books Network 167* Addiction with Gina Turrigiano (EF, JP)
Mar 26, 2026
Gina Turrigiano, neuroscientist and MacArthur Fellow who studies brain plasticity and sleep, joins to explore addiction from biological, anthropological, and literary angles. Short takes cover whether addiction is a habit or disease. They discuss neural ruts and recovery, how drugs fill social and emotional voids, shared brain reward pathways across behaviors, and distinctions between dependence and compulsion.
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Addiction As Compulsive Mental Habit
- Addiction is best understood as a habit of thinking and feeling that becomes compulsive through repetition and desire.
- Marc Lewis argues habit formation deepens neural 'ruts' and desire turns repetition into near-inevitable compulsion.
Neural Ruts Can Be Relearned
- Addiction involves reinforcement of neural pathways like ruts that deepen with repeated use but can be reshaped by forming new pathways.
- Gina compares pathways to road ruts: repetition deepens them, but new grooves can be learned with effort.
Drugs Shortcut The Same Pleasure Circuit
- Drugs take a shortcut into the same pleasure circuitry as non-drug rewards, making them more powerful but not categorically different.
- Opiates directly boost dopamine signaling, increasing potency and ease of addiction compared with behaviors like exercise.









