Changelog Master Feed Biocomputing on human neurons (Changelog Interviews #654)
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Aug 14, 2025 Ewelina Kurtys, a scientist and entrepreneur with a PhD in neuroscience, leads exciting biocomputing research at FinalSpark. She shares groundbreaking ideas about using lab-grown human brain organoids for computing, significantly improving energy efficiency. The discussion dives into the challenges of encoding information in neurons, parallels between neuronal and human learning, and the transformative potential of AI in neuroscience. Ewelina’s insights open up a brave new world, highlighting a future where biology and computing intricately collaborate.
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Ten-Year Road To Biocomputing
- Building useful biocomputers will likely take ~10 years because neurons' information encoding is still unknown.
- FinalSpark automated the lab to run many experiments and accelerate discovery by trial and error.
Probe Neurons With Electricity And Neurochemistry
- Use electrical stimulation and chemical modulation to program and probe neuronal behavior.
- Combine electrodes for input/output and add neurotransmitters like dopamine to shape learning.
One Bit Stored In Living Tissue
- The team has reproducibly stored a single bit by shifting a neurosphere's center of activity across electrodes.
- This is an early but concrete demonstration of information storage in living tissue.