
The Funk'tional Nutrition Podcast Understanding Autoimmunity Series: Triggers, Root Causes & Functional Labs | Ep 230
Nov 8, 2022
They unpack how infections, chemicals and a leaky gut can switch on autoimmunity. Short explanations cover molecular mimicry, bystander activation and microbiome diversity. They list functional lab options for immune, gut and toxin testing. Practical lifestyle basics like sleep, movement and blood sugar are highlighted before jumping into testing.
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Test Strategically With A Practitioner
- Do not order many functional tests at once; work with a skilled practitioner to interpret results and build a strategy.
- Erin Holt stresses testing is useless without contextual analysis and a staged plan tailored to symptoms and history.
Use Immune Reactivity Panels For Pathogens
- Consider immune-reactivity pathogen screens like Cyrex Array 12 when suspecting infectious triggers.
- Erin Holt highlights Array 12 detects immune responses to pathogens (Candida, H. pylori, EBV, etc.), which presence-on-stool alone cannot confirm.
Run Targeted Gut Tests
- Run functional GI testing (stool, SIBO breath, gut barrier) to assess dysbiosis, small-intestine overgrowth, and intestinal permeability.
- Erin Holt prefers GI-MAP for stool, IBS SMART for anti-vinculin, and Wheat Zoomer or Cyrex Array 2 for barrier and wheat reactivity.



