Practical AI in Healthcare S1, E3: Dr. Dereck Paul and Glass Health
Sep 14, 2025
Dr. Dereck Paul, physician-founder and CEO of Glass Health, builds LLM-based AI agents to help clinicians. He discusses using AI to synthesize EHR data and literature for diagnosis and treatment planning. He explains orchestrating focused, evidence-aware sub-agents and integrating with EHRs and ambient clinical workflows. He shares adoption progress and a vision of supervised AI agents improving care.
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AI At The Heart Of Clinical Care
- Dereck Paul founded Glass to bring modern AI into core clinical tasks like diagnosis and treatment at the point of care.
- He prioritizes clinical decision support over back-office automation to improve diagnosis and management quality.
Agent-Assisted Clinical Reasoning
- GLASS ingests EHR data and generates differentials, suggested diagnostics, and draft management plans for clinician review.
- Clinicians supervise and edit outputs, using the agent as a knowledgeable assistant rather than an autonomous decision maker.
Chained Agents Improve Contextual Answers
- Glass uses chained LLM agents (orchestrator plus specialized sub-agents) to search EHRs, literature, and compute results before synthesizing responses.
- That orchestration produces richer, case-specific outputs that outperform template-based notes.