Low Progesterone and DHEA Drive Psoriasis

Women with psoriasis consistently show lower progesterone and DHEA, two hormones that normally quiet inflammation, making flare-ups stronger and more frequent

Estrogen dominance — where estrogen feels too strong relative to progesterone — heightens immune reactivity and explains why symptoms worsen before your period, after childbirth and during menopause

Intracellular estrogen, not blood estrogen, drives inflammation in psoriatic skin, which is why your labs can look "normal" even when your symptoms intensify

Long-term hormone replacement therapy increases psoriasis risk by overstimulating inflammatory pathways, especially in post-menopausal women whose hormones are already shifting

You can ease flare patterns by supporting progesterone and DHEA, eliminating estrogen-mimicking triggers, avoiding seed oils, optimizing vitamin D and reducing stress-related hormonal strain