Osterholm Update Episode 190: Courage Over Fear
Aug 21, 2025
A tragic shooting at the CDC headquarters underscores the rising threats to public health officials. Discussion shifts to the courage these individuals show despite increasing hostility. The episode delves into the importance of mRNA vaccines and the implications of funding cuts for pandemic preparedness. Emerging threats from H5N1 avian flu and its alarming presence on dairy farms are highlighted. Misconceptions about vaccine adjuvants are addressed, emphasizing informed understanding in the vaccination debate. Resilience and empowerment in public health amid challenges complete the conversation.
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Vaccinate Immunocompromised With Caution
- Immunocompromised adults benefit from COVID and influenza vaccines but may have lower effectiveness; consider personalized risk assessment.
- For stem cell transplant patients, weigh RSV vaccine benefits against potentially lower efficacy and rare risks.
Early Signs Of Increasing COVID Activity
- CDC signals a modest national uptick in COVID via wastewater and ED visits, especially in children under 11.
- Osterholm expects rising cases but so far not a major surge in severe illness.
H5N1 Evidence On Dairy Farms
- A preprint found live H5N1 virus and viral RNA on dairy farms in air, wastewater, and milk, suggesting multiple farm transmission routes.
- Researchers recommend respiratory protection, strict disinfection, and isolating infected cows to reduce risk.
