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Medicine or Marketing? The Truth About HRT, GLP-1s, and Peptides with Dr. Robin Berzin

Mar 12, 2026
Dr. Robin Berzin, Columbia-educated, Mount Sinai-trained physician and founder of Parsley Health, offers a practical framework for sorting real health tools from hype. She tackles who truly benefits from GLP-1s, how to protect muscle during use, updated guidance on HRT for women, the clinical reality of peptides and psychedelics, and sensible uses for CGMs, microbiome tests, fasting, and cold therapy.
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ADVICE

Skip Consumer Microbiome Tests Use Clinical Panels When Needed

  • Do avoid consumer microbiome tests for the most part and use clinical-grade, doctor-prescribed stool panels when actionable diagnosis is needed.
  • Clinical tests can detect parasites, yeast, pancreatic dysfunction, fecal fat, calprotectin, and dysbiosis linked to Crohn's or colitis.
ADVICE

Use CGMs As Short Term Learning Tools Not Permanent Gadgets

  • Do use a CGM as a short-term tool to learn how foods affect your glucose but avoid chronic continuous use unless indicated.
  • Berzin used a CGM in pregnancy and prescribes it for patients who need insight to change diet after metabolic syndrome diagnoses.
INSIGHT

Starting HRT In Perimenopause May Be Protective

  • Reinterpreted WHI data and newer studies suggest HRT started in perimenopause reduces risks and may protect against osteoporosis, dementia, and even breast cancer.
  • Berzin cites a large records study showing up to 60% lower breast cancer rates when estrogen-progesterone begins in perimenopause.
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