Danny Jones Podcast #335 - Carnivore MD vs Harvard Heart Doctor: Seed Oils are Actually GOOD For You | Paul Saladino & Nick Norwitz
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Sep 26, 2025 
Dr. Nick Norwitz, a Harvard MD and PhD specializing in metabolic health, joins Dr. Paul Saladino, a nutrition expert known for his work on the carnivore diet. They dive into the controversies surrounding seed oils, challenging conventional wisdom and discussing their potential benefits. The duo critiques the flaws in medical research and the true causes of obesity, shifting the focus from calories to food quality. They also explore the connection between gut health and mental well-being, showcasing the complex dynamics of diet and metabolism.
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GLP‑1 Links Gut State To Metabolic Disease
- GLP‑1 deficiency links to metabolic disease and gut inflammation, making GLP‑1 a key hormonal target.
- Medications mimic GLP‑1 but upstream influences (microbiome, drugs) can deplete native levels.
RCTs Don’t Always Equal Best Care
- Evidence-based medicine and commercial incentives can diverge; what’s best physiologically may lack RCT support.
- Many promising, low-cost interventions remain under-researched because they don't attract pharmaceutical funding.
Statins May Lower GLP‑1 And Raise Blood Sugar
- Statins can cut GLP‑1 (an incretin hormone) by about half and worsen glycemic control in humans.
- Drug interactions can unintentionally impair metabolic hormones, showing the need to integrate metabolism into prescribing decisions.