Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast Episode 10: IV Induction Agents
Jul 19, 2016
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Prevent Propofol Infusion Syndrome
- Avoid propofol infusion syndrome by restricting doses below 70 mcg/kg/min for infusion periods under 48 hours.
- Monitor triglycerides for patients on prolonged high-dose infusions to prevent pancreatitis.
Barbiturates Offer More Cerebral Protection
- Barbiturates reduce cerebral metabolic rate and blood flow, more than propofol.
- This makes barbiturates more cerebral protective than propofol due to greater ICP reduction.
Benzodiazepine Uses and ECT Caution
- Use benzodiazepines for anxiolysis, amnesia, and seizure threshold elevation.
- Avoid benzos for ECT as they raise seizure threshold, impeding therapy effectiveness.