Episode 135 - Yerem Yeghiazarians - Co-Founder & CEO Soley Therapeutics

Today’s guest is Dr. Yerem Yeghiazarians — a leading interventional cardiologist, professor of medicine at the University of California, San Francisco, and a physician-scientist working at the cutting edge of cardiovascular innovation.

With medical training from Johns Hopkins and advanced cardiology specialization at Brigham and Women’s Hospital, Dr. Yeghiazarians has spent over two decades at UCSF treating complex heart disease and advancing the field of interventional cardiology.

Dr. Yeghiazarians is the co-founder of Soley Therapeutics, a biotech company focused on using AI to better understand how cells respond to stress, injury, and disease — with the goal of transforming how new drugs are discovered and developed.

Alongside this, he directs translational research exploring how stem cell therapies can repair heart damage after heart attacks, bridging fundamental science with real-world clinical impact.

From the cath lab to the biotech startup world, his career sits at the intersection of medicine, technology, and entrepreneurship — and today, we’ll explore that journey, the future of drug discovery, and what it takes to turn scientific insight into meaningful breakthroughs.