
ZOE Science & Nutrition Is your gut microbiome preventing weight loss? | Dr. Suzanne Devkota and Prof. Tim Spector
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Jan 9, 2025 Dr. Suzanne Devkota, Director of the Microbiome Research Institute, and Tim Spector, Professor of Epidemiology, delve into the fascinating world of gut bacteria and its crucial role in managing belly fat. They discuss how specific microbes can either support or hinder weight loss efforts and the complex relationship between visceral fat and immune health. Surprising insights reveal that the diversity of gut bacteria can impact overall well-being, and they share practical tips for improving gut health, including dietary changes and the benefits of fermented foods.
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Crohn's Disease Overview
- Crohn's disease, a type of IBD, affects the GI tract and is prevalent in Westernized societies.
- It involves chronic inflammation, pain, food avoidance, and frequent bowel movements.
Creeping Fat and Crohn's
- In Crohn's disease, bacteria translocate from the gut to the surrounding fat tissue.
- This "creeping fat" phenomenon is unique to Crohn's and guides surgical decisions.
Bacteria in Fat Tissue
- Bacteria found living in the fat tissue of Crohn's patients originated from the gut.
- These bacteria are genetically adapted to metabolize lipids.


