Blood Bank Guy Essentials Podcast 090CE: RHD Genotyping; We Can do Better! with Sue Johnson
May 19, 2021
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Clear Definition For Serologic Weak D
- Define serologic weak D as any initial typing ≤ 2+ or any discordant D result versus prior records.
- This clarifies who should be considered for RHD genotyping rather than ambiguous reporting.
Genotype Prenatal Weak D Cases
- Genotype pregnant and childbearing-age women who show serologic weak D or discordant D results.
- Use RHD genotyping results to guide RhIG administration and transfusion decisions.
Weak D Types 1–3 Behave Like D Positive
- Weak D types 1, 2 and 3 are common and rarely provoke anti-D formation.
- Treat those molecularly confirmed types as RHD positive for pregnancy and transfusion.