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History’s Largest Oil Disruption, Oil & AI, Sundar's New Pay Deal | Alex Epstein, Dr. Alex Wissner-Gross, Charles Lamanna, Julien Bek, Eoghan McCabe, Michelle Volz

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Mar 9, 2026
Michelle Volz, founder of PAX VC investing in foundational hard-tech. Alex Epstein, energy commentator analyzing Hormuz, oil shocks, and policy responses. Eoghan McCabe, Intercom CEO on FIN and expanding AI agents across customer lifecycle. Julien Bek, Sequoia partner on AI shifting software to outcome-driven models. Charles Lamanna, Microsoft exec on Copilot Cowork and enterprise agent platforms. Dr. Alex Wissner-Gross on fruit fly whole-brain upload progress.
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Uploading Humans Is Orders Of Magnitude Harder Than Flies

  • Human whole brain emulation is many orders of magnitude harder than a fly; humans have ~100–200 billion cells versus the fly's tiny network.
  • Progress requires a staged fidelity framework and intermediate 'levels' of uploading to evaluate risks and capabilities.

Invest In Multiple Paths To General Intelligence

  • Prepare for multiple technical paths to general intelligence: both transformer-style LLMs and biologically inspired spiking/net models can produce generality.
  • Build multidisciplinary programs that track progress across model classes rather than betting on one architecture.

Introduce Agents Inside Existing Office Workflows

  • Deploy Copilot Cowork by integrating agents where users already work (Office apps, Windows) and pair IT governance with user empowerment.
  • Use Agent 365 to centrally govern agents while enabling end users to adopt agentic workflows in-place.
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