The Top Line

Biopharma's rebound keeping pace so far

11 snips
Jan 30, 2026
Kristin Cirello Pothier, KPMG life sciences and global deal strategy leader, discusses the 2026 investment outlook. She reviews 2025 deal lessons, why cost discipline rose after COVID, and which early‑2026 acquisitions signal priorities. Conversations cover FDA uncertainty, manufacturing choices for smaller firms, and how valuations favor proven innovation.
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INSIGHT

2025 Fueled Portfolio Cleanup

  • 2025 saw lower deal volume but a focus on true innovation and portfolio right-sizing.
  • Companies prioritized cost-efficiency moves so they could be prepared for higher-quality deals in 2026.
ADVICE

Right-Size Operations Before Acquiring

  • Do prioritize cost discipline and automation before acquiring so you can integrate new assets without bloating costs.
  • Trim redundancies and optimize headcount to prepare for future acquisitions.
INSIGHT

Digital And Data Are Deal Multipliers

  • Early 2026 deals emphasize therapeutic innovation plus digital and data overlays.
  • Buyers now capture digital assets and data during diligence to ensure they transfer into the acquirer effectively.
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