Core Memory New, More Precise Cancer Therapies Could Soon Be Here - EP 51 Richard Fuisz
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Jan 12, 2026 
In this captivating discussion, guest host Arne Marrogi interviews Richard Fuisz, a biotech entrepreneur and scientist who founded Nonfiction Labs. They explore groundbreaking techniques using magnetically controllable proteins to enhance cancer therapies, potentially reducing harmful side effects. Richard shares insights on the challenges of DNA synthesis, his family's legacy in invention, and the competitive landscape of biotech between the U.S. and China. They even touch on the role of AI in protein design and the exciting future of therapeutics driven by magnetic technology.
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Directed Evolution Made Proteins Magnet-Sensitive
- Maria Ingramo ran directed evolution to make proteins respond visibly to magnets.
- After iterative mutation and selection, she produced proteins that visibly change color when a magnet is waved over them.
Magnetic Control Is Easier To Model Than Biology
- Magnetogenetics differs from optogenetics because magnets can be simulated and predicted with Maxwell's equations.
- That predictability could make targeting and dosing simpler than biology-driven targeting alone.
Activate Drugs Locally To Reduce Toxicity
- Turn drugs on locally to avoid systemic toxicity and enable risky targets.
- Use magnetic activation to make broadly expressed antigens viable by restricting activity to tumor sites.
