The Plant Free MD with Dr Anthony Chaffee Episode 330: Live Q&A with Dr Anthony Chaffee | Dec 15th, 2025
Jan 9, 2026
Dive into a lively Q&A where topics range from Michaela Peterson's upcoming trials on ketogenic diets to a new 90-day Carnivore Challenge. Discover how to get lean on a carnivore diet, explore the implications of rising LDL cholesterol post-keto, and learn about the potential pitfalls of processed sausages. Anthony discusses the carnivore diet’s benefits on skin health and energy, as well as strategies for improving athletic performance at any age. Plus, get tips on managing electrolytes and vitamin D levels while following this unique diet.
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Hormones Drive Fat Loss On Very High Fat
- Very high-fat, very-low-protein diets can trigger FGF21 and ketosis to increase energy expenditure by several hundred kcal/day.
- These hormonal shifts can explain fat-loss during extreme fat-focused protocols.
LDL Rise On Fat Metabolism Is Expected
- LDL often rises on ketogenic or carnivore diets because the body transports more fat using lipoproteins.
- Chaffee argues LDL itself isn't inherently harmful and lowering it by diet may not reduce cardiovascular deaths.
Weigh Drugs Against Diet Changes For LDL
- Discuss statins and other cardiac medications with your cardiologist and weigh pleiotropic benefits beyond LDL lowering.
- If concerned about high LDL, dietary carbs/plant fats will lower LDL but may not improve overall outcomes.