Mark Bell's Power Project

The Sugar Diet, Immune Cells & Why Diet Isn’t “Static” | Joel Greene

12 snips
Feb 18, 2026
Joel Greene, a nutrition and longevity researcher and coach, breaks down why the sugar diet can work short-term and how glycolysis, gut bacteria, and immune cell metabolism shift over time. He explores insulin complexity, carbohydrate sources, rhythmic pulses versus rigid routines, and practical eating patterns for long-term metabolic resilience.
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INSIGHT

Body Is A Dynamic Equilibrium

  • The body is not a static machine but a dynamic system chasing a shifting equilibrium.
  • Repeated dietary inputs produce curves over time, not fixed linear responses.
INSIGHT

Glycolysis Explains Sugar Diet's Quick Results

  • Sugar drives glycolysis which strongly promotes leanness in the short term.
  • But sugar also steers immune cell metabolism and can shift immune populations long-term.
INSIGHT

Sugar Source Shapes Gut Taxa

  • Different sugar sources feed different gut taxa and shift the microbiome composition.
  • Long-term sugar exposure can create overgrowths that produce unwanted outcomes.
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