Mastering Nutrition

Why do glycine and salt help with sleep? | Masterjohn Q&A Files #245

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Jul 29, 2021
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INSIGHT

How Glycine Promotes Sleep Physiology

  • Glycine likely works primarily as an inhibitory neurotransmitter and lowers core body temperature to help initiate sleep.
  • These physiological effects promote faster sleep onset and deeper sleep architecture.
ADVICE

Use Glycine And Salt At Bedtime

  • Take about 3 grams of glycine before bed to promote falling asleep faster and deeper sleep.
  • Use ~2 grams (about 1/2 teaspoon) of sodium chloride before bed to reduce nighttime urination by stimulating vasopressin.
INSIGHT

Sleep Is A Balance Of Competing Signals

  • Sleep and wakefulness result from the balance of many converging sleep and waking signals.
  • Strengthening sleep signals (like glycine's effects) makes you less likely to wake from other impulses like a full bladder.
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