
The Joe Rogan Experience #2491 - Brian Simpson
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Apr 29, 2026 Brian Simpson, comedian, writer, and Netflix special comic, dives into recovering from a heart attack with dark humor and wild hospital stories. Then it swerves into chaotic pet tales, urban coyotes and pythons, gaming obsession, nicotine habits, crypto scams, nightmare neighbors, and mind-bending space mysteries.
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Selective Breeding Changed Foxes Shockingly Fast
- Joe Rogan highlighted the Russian fox domestication experiment as a vivid example of how fast selective breeding reshapes animals.
- By breeding only the least aggressive foxes, researchers produced dog-like behavior plus physical changes like shorter snouts and floppy ears within generations.
Robot Rabbit Bait Accidentally Revealed Animal Highways
- Brian Simpson shared a python-control story where fake heated rabbit decoys failed but revealed that swamp predators follow hidden travel corridors.
- AI mapping of movement data suggested snakes and alligators use repeatable Everglades highways rather than moving randomly.
Brian Called A Reset After A Cartoonishly Bad Day
- Brian Simpson described a cursed day that started with his CPAP crashing, then a stubbed toe, then candle wax spilling onto light-colored pants.
- The wax looked like he had ejaculated on himself before a set, so he went home, napped, then returned later.






