Culture Apothecary with Alex Clark

The Biohacker’s Guide To Sleep, Nicotine, & Weight Loss | Dave Asprey

46 snips
Apr 10, 2026
Dave Asprey, entrepreneur and biohacking pioneer behind Bulletproof and Danger Coffee. He recounts dramatic weight loss origins, explains why calories aren’t the full story, and explores nicotine’s surprising therapeutic potential. Conversations cover sleep and circadian light control, peptides and nootropics, seed oils and mitochondrial harm, and practical biohacks for longevity and fertility.
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INSIGHT

How Industry Shaped Modern Nutrition Policy

  • Regulatory capture and industry influence shaped US dietary and medical systems, leading to monocultures of thought and suppressed natural therapies.
  • Dave traces historical influence to Rockefeller and institutional control of medical education and policy.
ANECDOTE

Biohacking Restored Natural Fertility

  • Dave used biohacking to restore his partner's fertility: removing estrogenic foods, optimizing thyroid, and gaining needed body fat.
  • She conceived naturally at 39 and 42 after diet and hormone-focused interventions without IVF.
ADVICE

Skip Mass Market Green Powders

  • Avoid buying generic green powders; they often mix many plant compounds that trigger sensitivities and offer little proven benefit.
  • Dave calls green powders a common wasteful supplement category that may provoke allergies.
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