The quest for Leonardo da Vinci’s DNA

In this episode of Science Quickly, host Kendra Pierre-Louis speaks with forensic scientist Rhonda Roby about an ambitious effort to uncover traces of Leonardo da Vinci’s DNA using modern forensic techniques. Roby and her colleagues are carefully sampling centuries‑old artworks, working with extremely small amounts of biological material, to learn more about Leonardo himself and the history of his art while also advancing methods that could one day help authenticate artworks. The episode explores how forensic approaches typically used in criminal investigations are being applied to a 500‑year‑old historical puzzle.

Recommended Reading:

The Race to Find Leonardo da Vinci’s DNA Just Took a Major Twist

“The real da Vinci code,” by Richard Stone, in Science, Vol. 391; January 8, 2026

E-mail us at sciencequickly@sciam.com if you have any questions, comments or ideas for stories we should cover!

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Science Quickly is produced by Kendra Pierre-Louis, Fonda Mwangi, Sushmita Pathak and Jeff DelViscio. This episode was edited by Alex Sugiura, with fact-checking by Shayna Posses and Aaron Shattuck. Our theme music was composed by Dominic Smith.

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