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460. Alzheimer’s is Now Optional: Root Causes, Prevention and Reversal with Dr. Dale Bredesen

Jul 20, 2023
Alzheimer's expert Dr. Dale Bredesen discusses root causes of and prevention methods for Alzheimer's disease. Topics include lifestyle factors, insulin resistance, neuronal health, cognitive decline prevention, and the KetoFLEX protocol.
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INSIGHT

Amyloid Is A Protective Response

  • Beta-amyloid is an adaptive antimicrobial peptide the brain makes in response to insults.
  • Removing amyloid without addressing root causes risks harm and misses the real problem.
ADVICE

Get A Cognoscopy At 40+

  • Get a 'cognoscopy' with blood tests and cognitive screening at age 40 or older.
  • Include MRI if you have symptoms and act early rather than waiting for dementia.
INSIGHT

APOE4 Reflects Evolutionary Tradeoffs

  • APOE alleles evolved and APOE4 was common in early hominids but now increases Alzheimer's risk in modern environments.
  • APOE4 carriers are hyper-responders who benefit greatly from targeted prevention.
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