The Science and Supply of GLP-1s

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Jun 19, 2024

Brooke Boyarsky-Pratt, the CEO of KnownWell, revolutionizes the obesity medicine landscape with her personal journey battling obesity. She discusses the critical role of obesity-specific practitioners and patient-centric medical homes in fostering trust. The conversation delves into the science and impact of GLP-1 medications, highlighting their tailored applications in treatment. The challenges of cost and supply in the obesity sector are addressed, alongside a vision for a more empathetic, comprehensive approach to obesity care.

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INSIGHT

GLP-1s Explained

GLP-1s mimic naturally occurring hormones, affecting insulin regulation, digestion, and fullness.
These therapies have been around since 2005, though recently gaining more public attention.

ANECDOTE

Early GLP-1 Awareness

Brooke first learned about GLP-1s in 2018 from an obesity medicine physician.
Dr. Fitch predicted the significant impact of GLP-1s in the future.

ADVICE

Managing GLP-1 Expectations

GLP-1s are effective but not a miracle cure, with varying weight loss results.
Manage expectations and address potential side effects like nausea with proactive measures.

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Brooke Boyarsky Pratt, founder and CEO of knownwell, joins Vineeta Agarwala, general partner at a16z Bio + Health.

Together, they talk about the value of obesity medicine practitioners, patient-centric medical homes, and how Brooke believes the metabolic health space will evolve over time.

This is the second episode in Raising Health’s series on the science and supply of GLP-1s. Listen to last week's episode to hear from Carolyn Jasik, Chief Medical Officer at Omada Health, on GLP-1s from a clinical perspective.

Listen to more from Raising Health’s series on GLP-1s:

The science of satiety: https://raisinghealth.simplecast.com/episodes/the-science-and-supply-of-glp-1s-with-carolyn-jasik

Payers, providers and pricing: https://raisinghealth.simplecast.com/episodes/the-science-and-supply-of-glp-1s-with-chronis-manolis

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