
The Egg Whisperer Show Treating Endometriosis Related Infertility with guest Dr. Geoffrey Sher
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Nov 11, 2025 Dr. Geoffrey Sher, a leading expert in assisted reproductive technology and co-founder of Sher Fertility Solutions, discusses the complex relationship between endometriosis and infertility. He explains that while endometriosis is a lifelong condition that cannot be cured, it can be managed effectively. Key insights include how pelvic toxins impact fertility, the role of IVF in bypassing these challenges, and the importance of timely egg retrieval for women with the condition. Dr. Sher further emphasizes the need for awareness regarding ovarian cancer risks associated with endometriosis.
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Use IVF To Bypass Pelvic Toxicity
- IVF bypasses the toxic pelvic environment by retrieving and fertilizing eggs before they encounter pelvic toxins.
- Consider IVF especially for women over 35 or with low ovarian reserve who lack time for low per-cycle conception chances.
How To Diagnose Endometriosis
- Definitive diagnosis requires visualization via laparoscopy or an ovarian endometrioma seen on ultrasound.
- Consider endometrial biomarker tests (e.g., BCL6) as supportive but not definitive evidence.
Remove Endometriomas Before IVF
- Remove ovarian endometriomas before IVF because they impair local follicle environment and egg chromosomal integrity.
- Treat endometriomas laparoscopically or with sclerotherapy to improve egg quality on that side.

