The TWiP-lets reveal Balamuthia infection in the Children from Peru, and discuss resistance to pyrethroids revealed by RNA sequencing of Anopheles mosquitoes.

Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin

Links for this episode:

Balamuthia (CDC)
Pyrethroid resistance in Anopheles (Parasit Vectors)
Voltage-gated sodium channels
Pyrethroid (Wikipedia)
Image credit
Letters read on TWiP 98

Case study for TWiP 98

This week's case is a Professor clinician, teacher, researcher. In his 50s, he presents with lesion on big toe, anterior portion, tip, nodular. No surrounding redness, area is itchy. Has a small central black area the size of pencil tip, concerned because feels is getting larger over last week. Spooky. Travels, last in Brasil, had been for a few weeks, noticed toe issue a week after returned. Spent time on beach, but wore flip flops. Different types of beaches, crowded and not crowded. Went with wife. Healthy man, no prior medical problems.

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TWiP 98: Resistance is not futile