The Global Story The ‘weight loss revolution’ changing the world
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Feb 11, 2026 
Giles Yeo, a Cambridge professor who studies how the brain controls eating and body-weight genetics, explores the rise of GLP-1 weight-loss drugs. He covers their biology and development, personal and family experiences, changing food industry and portion norms, access and equity concerns, and risks from side effects and misuse. The conversation examines cultural shifts around thinness and potential regulatory responses.
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Drugs Deliver Unprecedented Weight Loss
- GLP-1 drugs offer broadly safe, high-efficacy weight loss and diabetes control for many people.
- They can produce 15–25% weight loss, a level previously unimaginable at scale.
Personal Family Example Of Success
- Giles Yeo describes his son Harry starting a GLP-1 on Jan 1, 2025 after college weight gain.
- Harry forgot to eat sandwiches, lost about 55 pounds, and experienced no side effects.
Prepare Food Options When On GLP-1s
- If you start a GLP-1, plan simple healthy food options because the drug reduces food thinking.
- Stock easy proteins and vegetables so you can eat reasonably when hunger returns later in the day.