
Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas 112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering
Aug 31, 2020
Fyodor Urnov, a leading expert from UC Berkeley, dives into the revolutionary world of CRISPR technology. He discusses how gene editing can cure diseases like sickle cell and HIV, highlighting its transformative potential in medicine. Urnov also explores the ethical dilemmas of designer babies and the public's perception of genetic modifications. The conversation touches on the urgency of societal implications and the need for regulation as we navigate the future of human engineering.
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Future of Gene Editing
- Gene editing shows promise in treating cancer, genetic diseases, and chronic pain.
- Fyodor Urnov is excited about its potential for common diseases like cardiovascular disease.
Aging and Longevity Research
- Aging isn't recognized as a disease, hindering longevity clinical trials.
- Current research focuses on enhancing the body's defenses against damage.
Germline vs. Somatic Editing
- Germline editing, which affects future generations, should be banned due to ethical concerns and lack of medical necessity.
- Somatic editing, targeting specific cells in an individual, is acceptable with informed consent.



