Raising Health

Building AI Foundation Models for Molecular Design

17 snips
Jan 8, 2026
Jeremy Wohlwend and Gabriele Corso, co-founders of Boltz, delve into the transformative power of AI in molecular biology. They discuss Boltz’s mission to create open-source models that revolutionize biomolecular interaction and drug discovery. The conversation highlights breakthroughs post-AlphaFold, the rapid adoption of Boltz models by the pharma sector, and the launch of Boltz Lab—designed to streamline protein and small-molecule design in scientific workflows. They envision a future where AI accelerates iteration and enhances the drug discovery process.
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ADVICE

Productize Models For Real Labs

  • Move beyond GitHub: build products that let noncomputational scientists use the models in workflows.
  • Invest in engineering, security, and enterprise support to scale real-world impact.
ADVICE

Treat Discovery Like Infrastructure

  • Treat molecule discovery as heavy infrastructure: provision large compute and parallelize workflows to shorten turnaround.
  • Build engineering teams focused on scaling inference and search across molecular space.
INSIGHT

PBC Status Embeds The Mission

  • Incorporating a public benefit charter locks the mission to widen access to frontier biomolecular AI.
  • Boltz sees the PBC status as a permanent reminder aligning commercial goals with open accessibility.
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