Ep. 582 PERT Consortium Recap: New Developments in PE with Dr. Jonathan Paul and Dr. Osman Ahmed

15 snips

Oct 17, 2025

Dr. Jonathan Paul and Dr. Osman Ahmed, experts in interventional cardiology and radiology, share insights from the recent PERT Consortium in San Diego. They delve into cutting-edge developments in pulmonary embolism (PE) treatment, including advancements in thrombectomy devices and the importance of combined therapies. The conversation also highlights their collaboration at Flow Medical, focusing on a novel device that provides real-time pulmonary artery pressure feedback. Their passion for innovation and data-driven approaches promises a transformative future for PE care.

Ask episode

AI Snips

Chapters

Transcript

Episode notes

INSIGHT

Big Acquirers Are Shaping Device Access

Major acquisitions (e.g., Inari by Stryker) signal large-company interest and will shape which devices hospitals can stock.
Market consolidation and contracts will influence real-world device availability.

ANECDOTE

Flow Born From Cardiology–IR Collaboration

Jonathan Paul and Osman Ahmed formed Flow by bridging cardiology and IR silos and combining complementary skills.
They emphasize treating the entire pulmonary vasculature and minimizing residual occlusion after intervention.

INSIGHT

Real-Time PA Pressure–Guided Thrombolysis

Flow prioritizes precision thrombolysis guided by real-time pulmonary artery pressures to tailor dosing and duration.
Their device integrates a fiber-optic PA pressure sensor to stop dosing at diminishing returns.

Get the Snipd Podcast app to discover more snips from this episode

Get the app

PERT Consortium 2025 gives interventionalists the reins to tackle even the toughest saddle pulmonary embolisms. In this episode of the BackTable Podcast, host Dr. Aaron Fritts welcomes interventional radiologist Dr. Osman Ahmed and interventional cardiologist Dr. Jonathan Paul to discuss their experiences at the annual PERT Consortium in San Diego, and offer their perspectives on the latest developments in pulmonary embolism (PE) treatment.
---
SYNPOSIS
The doctors delve into advancements and trials within the PE treatment space, including new devices and clinical studies that are set to shape the future of pulmonary embolism care. The conversation highlights the value of collaboration between interventional specialties, the safety and efficacy of various PE interventions, and the growing trend of using combined therapies. They also provide updates on their ongoing innovation with Flow Medical, describing their philosophy and motivation for developing a new device for PE treatment that incorporates real-time pulmonary artery pressures, mean systolic and diastolic pressures, and a potential for AI utilization in the future.
---
TIMESTAMPS
00:00 - Introduction
01:23 - PERT Consortium Highlights
02:11 - Emerging Clinical Trials and Innovations
03:59 - Thrombectomy Devices and Market Trends
12:37 - Flow Medical: Origin and Updates
19:37 - Advanced Data Tracking in Cardiology
20:45 - Remote Monitoring and Mobile Integration
22:45 - Cardiologists’ Data-Driven Approach
23:10 - Upcoming Studies and Data Insights
24:10 - Interventional Radiology and Cardiology Collaboration
25:07 - Access to Care and Procedure Adoption
27:32 - Final Thoughts
---
RESOURCES
Pulmonary Embolism Response Team (PERT) Consortium
https://pertconsortium.org/
Flow Medical
https://www.flowmedical.co/
PEERLESS RCT
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.124.072364
RESCUE-II
https://www.jacc.org/doi/10.1016/j.jacadv.2025.101789
PEERLESS II
https://www.jscai.org/article/S2772-9303(24)01053-6/fulltext
Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy (PE-TRACT)
https://clinicaltrials.gov/study/NCT05591118
The HI-PEITHO Study
https://www.bostonscientific.com/en-EU/medical-specialties/vascular-surgery/venous-thromboembolism-portal/pulmonary-embolism/clinical-data/hi-peitho.html
PRAGUE-26
https://eurointervention.pcronline.com/article/design-and-rationale-of-prague-26-a-multicentre-randomised-trial-of-catheter-directed-thrombolysis-for-intermediate-high-risk-acute-pulmonary-embolism
Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy (PE-TRACT)
https://clinicaltrials.gov/study/NCT05591118
Aaron Fritts, MD
https://www.backtable.com/shows/vi/contributors/dr-aaron-fritts
Osman Ahmed, MD
https://jointvascular.com/team/osman-ahmed-m-d-fcirse/
Jonathan Paul, MD
https://www.uchicagomedicine.org/find-a-physician/physician/jonathan-d-paul